Migraine - Prophylactic treatment
10 important questions on Migraine - Prophylactic treatment
What patients should migraine prophylaxis be considered for?
How is a migraine prophylactic drug chosen?
Trial of min of 8 weeks, then switch if no response. Continue x6-12 mo if partial response.
Antihypertensives for migraine prophylaxis
alt: lisinopril, candesartan
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Migraine prophylaxis + interested in weight loss
Contraception for simple migraine (no aura)
Contraception for migraine + aura
Beta blocker warnings and side effects
Bradycardia, hypotension, impotence, CNS effects (fatigue, dizzy, depression - more with propranolol, the most lipophilic), cold extremities (exacerbate Raynauds)
Divalproex and valproic acid BBW and warnings/side effects
Weight gain>loss, thrombocytopenia, alopecia, increased ammonia
Topiramate warnings and side effects
Weight loss, somnolence, cognitive impairment, reduced efficacy of PO contraceptives
If only 2 CGRPs are PO, what form are the remaining CGRPs?
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