Common skin conditions

67 important questions on Common skin conditions

What is the primary determinant of acne?

Androgen activity (male sex hormone)

How do retinoids work?

Reduce the stickiness of follicular epithelial cells, to unblock pores and prevent acne

What is first line for mild acne?

Topical benzoyl peroxide or retinoid
OR topical combo
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What is an alternative first line for mild acne?

Add topical retinoid or BPO, switch to another retinoid or topical dapsone

What is 1st line for moderate acne?

Topical combo
OR
PO abx + BPO + topical retinoid (+/- topical abx)

What is an alternative 1st line for moderate acne?

Another combo, or
switch PO abx, or
add combined OCP or spironolactone (females) or isotretinoin

What is 1st line for severe acne?

Topical combo + PO abx
OR
PO isotretinoin

What is an alternative for severe acne?

Switch PO abx, or
add combined OCP or spironolactone (females) or PO isotretinoin (if not tried already)

What are the topical combo options?

BPO + topical abx
BPO + retinoid
BPO + topical abx + retinoid

How should topical retinoids be applied?

Pea-sized amount daily, at bedtime, about 20 minutes after washing face

How should topical retinoids be applied if causing irritation?

Use lower strength or use every other night.
Avoid salicylic acid scrubs/astringents. 

How long does it take to see response of topical retinoids?

4-12 weeks
acne may get worse at first 

Isotretinoin capsules is only FDA approved for what type of acne?

Severe, refractory nodular acne

Do not get pregnant for how long before taking, or how long after stopping isotretinoin?

1 month before
1 month after

What must be done before starting isotretinoin if the patient is able to get pregnant?

Sign consent form about birth defects & have 2 negative pregnancy tests

How is isotretinoin dispensed?

REMS (iPLEDGE) program
1-month Rx at a time 

What does isotretinoin cause in some females?

Severe inflammatory acne

Isotretinoin counseling points

Repeat pregnancy tests monthly
2 forms of birth control (cannot use progestin-only pill) 

What are the PO abx for acne?

Minocycline (Minocin, Solodyn)

Herpes simplex labialis "cold sores" are caused by what and spread how?

Herpes simplex virus type 1 (HSV-1); spreads mostly with active lesions, kissing & sharing drinks

What is the natural product used to prevent & treat cold sores?

Lysine

What is the OTC treatment for cold sores that should be applied 5x daily at the first sign of outbreak?

Docosanol (Abreva)

What is the Rx treatment for cold sores that should be applied 5x daily for 4 days?

Acyclovir topical cream/ointment (Zovirax)

What is a mild form of seborrheic dermatitis that involves the scalp, with white, itchy flakes of dead skin cells in the hair?

Dandruff

How should the 1st line OTC for dandruff be applied?

Ketoconazole 1% shampoo (Nizoral A-D) twice weekly for up to 8 weeks.
do not use if open sores on scalp. 

How should the 2nd line Rx for dandruff be applied?

Ketoconazole 2% shampoo (Nizoral)
rub shampoo in well, leave in for 5 min, then rinse out 

What drug for alopecia (hair loss) is a 1 mg tablet taken daily that can take >3 months to see effects, and is contraindicated in pregnancy?

Finasteride (Propecia)

What is the other name for Finasteride that is used for BPH?

Proscar

What is the topical drug used for alopecia (hair loss)?

Minoxidil topical (Rogaine)

Eczema (atopic dermatitis) appears how and mainly affects what areas?

Itchy, red, dry skin rashes, may turn into crusty, scaly sores.
Elbows, behind knees/ears, face, butt, hands, feet

What OTC moisturizers can be used to reduce eczema severity?

Petrolatum & lanolin (aquaphor, eucerin)

1st line for eczema

Topical steroids

2nd line for eczema

Topical calcineurin inhibitors

What should be done after applying any topical products for eczema?

Wash hands

Topical calcineurin inhibitors counseling points

Do not use in kids <2 yrs old
Associated with lymphoma and skin cancer

Avoid exposure to natural/artificial sunlight

What are the topical calcineurin inhibitors?

Tacrolimus (Protopic) ointment
Pimecrolimus (Elidel) cream

Diaper rash can be prevented with skin protectants:

Petrolatum ointment
Petrolatum with zinc oxide (a desicant) [Desitin, Boudreax's butt paste]

Diaper rash can be treated with:

Clotrimazole, miconazole
If stubborn & yeast: nystatin

What drug is a vasoconstrictor that shrinks the hemorrhoid and reduces burning/itching?

Phenylephrine (Preparation H)

What is used for treatment of pinworms (vermicularis)?

OTC pyrantel pamoate

What is typically OTC 1st line for lice?

Pyrethrin/piperonyl butoxide (RID)
Permethrin 1% lotion (Nix

What drug is an organophosphate only for 6 years and older, used for lice? It can cause skin irritation and is flammable.

Malathion lotion 0.5% (Ovide)

When should 1st line treatment for lice be repeated?

Repeat treatment on day 9

After lice treatment, how often should a nit comb be used to remove nits and lice?

Every 2-3 days

Which Rx drug is an antibiotic cream or ointment with very good staph & strep coverage, including MRSA?

Mupirocin (bactroban)

What is an allergic reaction that results from touching the sap of plants, which contain the toxin urushiol?

Poison ivy, oak, or sumac poisoning

What can be done to help with poison ivy symptoms?

Cold compress, attempt to remove toxin (wash skin with soap, water)
Topical or PO steroids-if severe rash

What OTC drugs can be used for poison ivy?

Colloidal oatmeal (Aveeno)
Calamine lotion (Caladryl)

What are the two OTC strengths of hydrocortisone?

0.5% and 1%

What drug is used for general urticaria (hives) with severe itching?

Hydroxyzine (Vistaril)

"fingertip" unit (fingertip to the 1st joint) is used to measure estimate amounts and provides how much medication?

Enough to cover one adult hand (~ 1/2 gram)

Very high potency topical steroids

Clobetasol propioinate 0.05%
Fluocinonide 0.1% cream (Vanos)
Halobetasol   

High potency topical steroids

Betamethasone dipropioniate 0.05% cream
Fluocinonide 0.05% ointment

Mometasone furoate 0.1% ointment

High-medium potency steroids

Fluocinonide 0.05% cream

Medium potency steroids

Mometasone furoate 0.1% lotion
Triamcinolone acetonide 0.1% cream & spray (Kenalog)

Lowest potency steroids

Hydrocortisone cream:
0.5%
1% (Cortizone-10) 

Best for thick or dry skin to give the best moisture barrier

Ointment

Topical that is less potent than ointments

Creams

Best topicals for hairy skin

Lotions, gels, foams

UV that causes damage below skin surface

UVA
(A= aging) 

UV that causes the skin to burn

UVB
(B=burning) 

What type of sunscreen protects against both UVA and UVB?

Broad spectrum sunscreen

How should babies less than 6 months old be protected from the sun?

Keep them out of the sun

What can sunscreens claim to be for 40-80 minutes?

"water-resistent"

Time To Burn (with sunscreen in mimutes)=

SPF x TTB (w/o sunscreen)

What are the recommended physical sunscreens?

Zinc oxide & titanium dioxide

If avoiding the sun, what supplement may be needed?

Vitamin D

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