Learning Goal - My lesson notes - cocca

29 important questions on Learning Goal - My lesson notes - cocca

Classification of staphylococcus aureus


GS: gram (+)
MR: cocci in grape-like clusters
MT: nonmotile
AR: facultative anaerobe

Toxic shock syndrome toxin - 1

Toxic Shock Syndrome ;
  • commonly attributed to the prolonged usage of tampons during menstruation
  • present with fever, hypotension, rash

Characteristic of Streptococcus pyogenes

  • opportunistic pathogen
  • Beta hemolytic (make the area clear = completely destroy red blood cells)
  • catalase (-)
  • facultative anaerobic
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Classification Streptococcus pyogenes

GS: Gram (+)
MR: Cocci in chains
MT: nonmotile
AR: facultative anaerobe

Reservoir of Streptococcus pyogenes

upper respiratory tract
indigenous microbiota

Transmission of Streptococcus pyogenes

respiratory droplets
indirect contact thru fomites (non living things)

Virulence factors of Streptococcus pyogenes


  • Erythrogenic toxin
  • Streptolysin O
  • Exotoxin B
  • M protein
  • fibrinolysin (streptokinase) - when surrounded, it produce to break down

Virulence factors of streptococcus pyogenes (toxins)

  • Erythrogenic toxin (scarlet fever)
  • Streptolysin O (pharyngitis) or (tonsillitis)
  • Exotoxin B (necrotizing fasciitis) - infection for muscle
  • M protein (streptococcal pharyngitis sequelae) - consequence after getting tonsillitis
  • Exotoxin B  (necrotizing fasciitis - flesh eating disease)

Type of a disease that produces an autoimmune response to the proteins found on the joint, heart and brain thru MOLECULAR MIMICRY

Rheumatic Fever

What organ does the Rheumatic Fever focuses to target

Joint, heart, brain

A disease that M protein incites immune complex deposition on renal tubules

post-Streptococcal Glomerulonephritis

What organ does the post-Streptococcal Glomerulonephritis focuses on

renal tubules

Characteristic of streptococcus pneumonia

opportunistic pathogen
alpha hemolytic (makes the surrounding to become green)
sensitive to optochin (antibiotic)
catalase (-)

Classification of Streptococcus pneumonia

GS: Gram (+)
MR: "lancet shaped" diplococci
MT: nonmotile
AR: facultative anaerobe
O: encapsulated (surrounded by capsule)

Disease that can get of streptococcus pneumonia

  1. Pneumonia - inflammation of lung parenchyma wherein the air sacs may be filled with fluid or pus thus impeding gas exchange
  1. Otitis media - infection of middle ear
  2. Bacterial Meningitis - infection of meninges
  3. Sinusitis - most common in maxillary and frontal sinuses

Prevention of having streptococcus pneumonia

Pneumococcal vaccine

Characteristics of Streptococcus Viridans

Opportunistic pathogen
Alpha Hemolytic or
Non-Hemolytic
CATALASE (+)
Does not grow on bile
RESISTANT TO OPTOCHIN

Reservoir of streptococcus viridian (MTCF)

mouth, throat, colon, female genital tract

Virulence factor of streptococcus viridans

Dextran - this will bind to the heart valves and the different tissues


Biofilm - organic matter that prevents antibiotics from penetrating

disease of streptoccocus viridian that this will bind to the heart valves and the different tissues

Dextran

Disease of streptococcus viridans that organic matter will prevents antibiotics from penetrating

Biofilm

Classification of neisseria gonorrhoeae

GS: Gram (-)
MR: Kidney bean shaped diplococci
MT: nonmotile
AR: microaerophilic
O: with pili

Diseases that can get of Neisseria gonorrhoeae

  1. Gonorrhea
  • An STI involving mucosal lining of GUT, rectum,
  • pharynx that may present with
  • painful urination and vaginal/penile discharge
  1. Ophthalmia neonatorum
  • conjunctivitis of the newborn as a result of exposure to gonococcus in the birth canal - that's why at birth babies' eyes are giving Gentamicin to prevent this.

This medicine gives for the birth babies that have  Ophthalmia neonatorum to prevent this

Gentamicin

Classification of Neisseria meningitidis

GS: Gram (-)
MR: Kidney bean shaped diplococci
MT: nonmotile
AR: aerobic
O:  encapsulated and with pili

Transmission of Neisseria meningitidis

respiratory droplets
high carriage state in close quarters (military, dorms, camps)

Virulence factor of Neisseria meningitidi

capsule
endotoxin

Diseases that can get of  Neisseria meningitidis

Bacterial meningitis
  • infection of the meningitis and may spread to the brain; presents with fever, neck rigidity, vomiting & altered consciousness or coma
Respiratory infections
Meningococcemia
  • dissemination of meningococci in bloodstream
    spread all over the blood
  • Starts with nasopharyngitis → ecchymotic hemorrhages (skin bruising)

Prevention of Neisseria meningitidis

appropriate antibiotics therapy
Prophylaxis for those exposed HCWs
vigorous supportive care
meningococcal vaccine
assess neurologic signs
strict aseptic technique, isolation is necessary
check that the patients are sleepy 

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