2015 Final, Koch & Robertson
51 important questions on 2015 Final, Koch & Robertson
In the multilayered bell stage of the developing tooth, the enamel organ consists of
Which of the following tissues arises from cells passing through the primitive streak?
What substance suppresses paramesonephric duct formation?
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The sclerotome arises from cells that were located in the
Which layer of the bilaminar embryo gives riese to all of the embryonic tissue proper?
At what stage in the life history of many cells are cell adhesion molecules lost?
Sonic hedgehog is produced in which of the following signaling centres or tissues?
A dog is born with syndactyly. What is the likely immediate reason for this anomaly?
The signaling molecule Wnt-4 is crucial for female sexual development. Consider an animal that is null mutant for the Wnt-4 gene. What would be the consequence of this mutation to reproductive system development?
Which is not a derivative of the neural crest?
A male calico cat is most likely to be
In which state will the chromatin be condensed (heterochromatinized) and DNA unreadable, leading to a state of transcriptional silence?
A 6 year old female spayed Labrador Retriever is presented to the veterinarian and you with an enlarged left prescapular (superficial cervical) lymph node. A fine needle aspirate of the prescapular lymph node is examined cytologically and reveals a monomorphic population of large blastic lymphocytes. This enlarged lymph node is most likely due to (choose one)
An 8 year old male neutered Siamese has diarrhea, occasional vomiting, and weight loss. A biopsy of the cat's intestine reveals lymphocytes which the pathologist cannot with a certainty diagnose as cancer. The astute student veterinarian suggests the lymphocytes can be sent to a laboratory for a clonality test (also known as a polymerase chain reaction for antigen receptor rearrangements [PARR] test) if the clonality test reveals only one band then the clinicians will diagnose (choose one)
A 6 year old female spayed Scottish Terrier is presented to the veterinarian and you with hematuria (blood in her urine), pollakiuria (increased frequency of urination), and stranguria (straining to urinate). The dog is subsequently diagnosed with transitional cell carcinoma (TCC) which is a cancer of her lower urinary tract. The owner notes that a group of closely related Scottish Terriers in different homes is having more cancer than expected! You hypothesize the most likely mechanism for the increased incidence of cancer in this group of scottish terriers is (choose one)
A 1 year old intactmale cat is presented for dyspnea (difficulty breathing) to the veterinarian and you. Together, using cytological examination of fluid from the cat's thorax, you diagnose a mass in the cat's chest as lymphosarcoma. Using an ELISA (enzyme-linked immunosorbent assay) blood test you also diagnose the cat is feline Leukemia Virus positive! You hypothesize the Feline Leukemia virus caused the lymphosarcoma by (choose the most likely mechanism)
Cancer in dogs and cats is similar to cancer in people (choose ONE)
In animals and people, the most common cause of cancer is (SELECT ONE)
Tyrosine kinase inhibitors (TKIs) such as Palladia (toceranib) are:
Artificial selection for egg production has resulted in a reduction in broodiness in laying hens. This behavioural change is an example of
Beef cattle show better maternal behaviour than dairy cattle - which of the following is the suggested mechanism?
Which of the following is a common effect of domestication on behaviour:
Canine aggression is a complex behaviour thought to be mediated by
Flank sucking is an abnormal repetitive behaviour that is most likely to be seen in:
Friendliness in kittens has been found to be related to which of the following
Numerous studies across a variety of species suggests effects of coat colour on reactivity and aggression. Which of the following is a possible mechanism that has been proposed to explain these coat-colour effects?
Which statement is TRUE for molecular diagnostic tests of nucleic acid
Which test for feline ringworm has the LOWEST risk of a FALSE positive result?
Mendel's second law of independent assortment has to do with
Hereditary equine regional dermal asthenia (HERDA) is due to a defect in the gene:
Bovine syndactyly (mulefoot) is an
Bovine leukocyte adhesion deficiency (BLAD) is mostly observed in the breed
By which mode of inheritance is bay coat color in horses inherited?
Roan, Overo-spotting and Tobiano-spotting inhorses all belong to the coat color phenotype categorized as:
Ichtyosis congenital is a disorder of
Pigmentation of skin and hair broadly depends on the ratio of eumelanin and pheomelanin, the two components of melanin. Which statement is correct:
Inherited disorders in cats include (choose only ONE answer)
By which 3 properties are a stem cell defined?
In which of these areas may stem cells be applied or utilized
Hematopoietic stem cells used for leukemia therapy have been shown to be true stem cells by the following methodology:
Multipotent mesenchymal stromal cells (MSC) are characterized by
Embryonic stem cells are isolated from
The transcription factors Oct3/4, Sox2, Klf4, and C-Myc are collectively known as:
Allognic/allogeneic cells are defined as
Choose the most appropriate answer. Engineering of tissues relies on the interplay of:
Stromal vascular fraction refers to
Multimodal administration of cells refers to
In order to evaluate the efficacy of stem cell therapies studies need to account for
Multipotent mesenchymal stromal cells may exert their function by
Induced pluripotent stem cells are more suitable for personalized medicine than embryonic stem cells
Embryonic stem cells cannot be generated from living individuals
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