Summary: Essentials Of Medical Pharmacology | 9789350259375 | KD Tripathi
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2 Drugs Acting on Autonomic Nervous System
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2.1 Autonomic Nervous System: General Considerations
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What regulates autonomic functions in the autonomic nervous system?
The highest regulation occurs in the hypothalamus, involving sympathetic and parasympathetic nuclei. -
Where are the cell bodies of autonomic afferent fibres located?
They are located in the dorsal root ganglion and sensory ganglia of cranial nerves. -
What kinds of reflexes do autonomic afferents mediate?
They mediate visceral pain and various visceral reflexes, including cardiovascular and respiratory. -
What divides the motor limb of the autonomic nervous system?
It is divided into sympathetic and parasympathetic pathways for organ innervation. -
What is the function of neurohumoral transmission?
Nerves release chemical messengers to transmit messages across synapses and neuroeffector junctions. -
Which substance was proven to be a vagal transmitter in 1926?
Acetylcholine was determined to be the vagus substance released during stimulation. -
What modulates the release process of neurotransmitters?
The release can be modulated by the transmitter itself and other agents activating specific receptors. -
How does an excitatory postsynaptic potential (EPSP) occur?
An EPSP happens due to increased permeability to cations, causing depolarization in the membrane. -
What terminates the action of neurotransmitters?
The transmitter is degraded, reuptaken, or diffuses away after binding to receptors. -
What does cotransmission imply about neurotransmitter release?
Many neurons release more than one active substance, complicating the one-neurotransmitter model.
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