Geriatric Bipolar Mood Disorder

5 important questions on Geriatric Bipolar Mood Disorder

Pathogenesis of Bipolar Mood Disorder in Older Adult

It may be related to VASCULAR (BLOOD-VESSEL) CHANGES in the brain.

white matter hyperintensities (results of deficits in vascular perfusion)
Increased temporal lobe volume from MRI f

Organic cause of Bipolar Mood Disorder in Older Adult

Multiple Sclerosis
HIV
Head injury
Hyperthyroidism

Drug induced mania

1. steroids for arthritis, asthma, or inflammatory bowel disease
2. dopaminergic drugs for Parkinson disease
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Key Clinical Differences between Older Adult BMD and young onset

more common and severe.
Cognitive impairment
Medical illnesses
Psychotic features in the depressive phase.
Presence of neurological disorders.  

less common
Comorbid anxiety and substance use disorders
Manic episodes less severe.
Excessive sexual interest and behavior less common.

Cut off age early onset BMD and late onset BMD

50 years

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