Summary: Honors Biology

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  • What is the first step in the path of a secretory protein through the rough endoplasmic reticulum?

    • The ribosome begins to produce the polypeptide.
    • The first few amino acids are called a "signal peptide."
    • The signal peptide helps direct the ribosome to the Rough Endoplasmic Reticulum's surface.
  • What are the two types of endoplasmic reticulum and their purposes?

    • Rough ER: Attached to the nuclear membrane, studded with ribosomes, modifies and folds proteins.
    • Smooth ER: Lacks ribosomes, helps produce hormones and lipids.
  • What happens after the signal peptide enters the rough endoplasmic reticulum's membrane?

    • The ribosome continues building the polypeptide.
    • As it is built, it passes through the membrane and enters the endoplasmic reticulum's lumen.
  • What is the function of the rough endoplasmic reticulum?

    • Series of folds dotted with ribosomes.
    • Continuous with the nuclear envelope.
    • Vesicles travel from the rough ER to the Golgi apparatus.
  • How are proteins modified in the rough endoplasmic reticulum?

    • Proteins enter the rough ER to be modified and folded.
    • They are transported to the Golgi for further modification.
    • Ribosomes on the rough ER surface aid in protein folding.
  • Describe the modification process of the polypeptide inside the rough endoplasmic reticulum's lumen.

    • The signal peptide has been removed.
    • The rest of the polypeptide is fully inside the ER's lumen.
    • The polypeptide is modified.
  • What is the Golgi apparatus present in, and how many Golgi does each cell have?

    • Present in all known eukaryotic cells.
    • Each cell has many Golgi.
    • Each Golgi has 4-8 cisternae.
  • What is the function of the smooth endoplasmic reticulum?

    • Lacks ribosomes.
    • Produces hormones and lipids.
    • Involved in detoxification processes.
    • Found in high amounts in reproductive organs and glands.
  • What occurs after the ribosome finishes building the protein?

    • The ribosome releases the protein.
    • The ribosomal subunits float away from the rough ER's surface.
  • What is the primary role of the mitochondrion in eukaryotic cells?

    • Produce ATP
    • Known as the "powerhouse" of the cell
    • ATP carries energy like a battery
    • Inner membrane folded into cristae
    • Contains ribosomes and DNA
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