Summary: Honors Biology
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1 Learning Goal 1
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What is the first step in the path of a secretory protein through the rough endoplasmic reticulum?
- The ribosome begins to produce the polypeptide.
- The first few amino acids are called a "signal peptide."
- The signal peptide helps direct the ribosome to the Rough Endoplasmic Reticulum's surface.
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What are the two types of endoplasmic reticulum and their purposes?
- Rough ER: Attached to the nuclear membrane, studded with ribosomes, modifies and folds proteins.
- Smooth ER: Lacks ribosomes, helps produce hormones and lipids.
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What happens after the signal peptide enters the rough endoplasmic reticulum's membrane?
- The ribosome continues building the polypeptide.
- As it is built, it passes through the membrane and enters the endoplasmic reticulum's lumen.
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What is the function of the rough endoplasmic reticulum?
- Series of folds dotted with ribosomes.
- Continuous with the nuclear envelope.
- Vesicles travel from the rough ER to the Golgi apparatus.
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How are proteins modified in the rough endoplasmic reticulum?
- Proteins enter the rough ER to be modified and folded.
- They are transported to the Golgi for further modification.
- Ribosomes on the rough ER surface aid in protein folding.
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Describe the modification process of the polypeptide inside the rough endoplasmic reticulum's lumen.
- The signal peptide has been removed.
- The rest of the polypeptide is fully inside the ER's lumen.
- The polypeptide is modified.
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What is the Golgi apparatus present in, and how many Golgi does each cell have?
- Present in all known eukaryotic cells.
- Each cell has many Golgi.
- Each Golgi has 4-8 cisternae.
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What is the function of the smooth endoplasmic reticulum?
- Lacks ribosomes.
- Produces hormones and lipids.
- Involved in detoxification processes.
- Found in high amounts in reproductive organs and glands.
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What occurs after the ribosome finishes building the protein?
- The ribosome releases the protein.
- The ribosomal subunits float away from the rough ER's surface.
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What is the primary role of the mitochondrion in eukaryotic cells?
- Produce ATP
- Known as the "powerhouse" of the cell
- ATP carries energy like a battery
- Inner membrane folded into cristae
- Contains ribosomes and DNA
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