Book summary - core DNA technologies
4 important questions on Book summary - core DNA technologies
Nucleic acid hybridization assay?
- A probe population often labbeld with fluorphore is used to interrogate the test sample.
- With small probes you can identify alleles that differ by a single nucleotide. Base mismatc
h are not tolerated.
- With long probes you can identify similarity, the hybridization can tolerate base mismatching.
Chromosome in situ hybridization?
- FISH on of them.
ABI SOLiD technique?
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Ion Torrent systems
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