Summary: Meningiomas
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1 Meningiomas
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Meningiomas account for ~what percent of non-malignant CNS tumors?
~54%. -
Meningiomas are the most common NON-GLIAL neoplasm of the CNS — true/false?
TRUE. -
Typical demographic association for meningiomas?
FEMALE PREDOMINANCE, usually 5TH DECADE. -
List 3 major etiologic associations for meningiomas.
SPORADIC, NF2, POST-RADIATION (XRT-INDUCED). -
Cell of origin (board phrasing): meningiomas arise from what cells?
MENINGOTHELIAL / ARACHNOID CAP CELLS. -
Why can meningiomas occur “anywhere” in brain/spine?
Arachnoid cap cell rests exist THROUGHOUT THE CNS. -
WHO meningioma grades?
GRADE 1 / GRADE 2 / GRADE 3 (typical / atypical / anaplastic). -
Mitotic cutoff for GRADE 1 meningioma (per notes)?
< 4 mitoses per high-power field. -
Mitotic range for GRADE 2?
4–20 mitoses/HPF. -
Mitotic cutoff for GRADE 3?
> 20 mitoses/HPF.
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