Summary: Meningiomas

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  • 1 Meningiomas

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  • Meningiomas account for ~what percent of non-malignant CNS tumors?

    ~54%.
  • Meningiomas are the most common NON-GLIAL neoplasm of the CNS — true/false?

    TRUE.
  • Typical demographic association for meningiomas?

    FEMALE PREDOMINANCE, usually 5TH DECADE.
  • List 3 major etiologic associations for meningiomas.

    SPORADIC, NF2, POST-RADIATION (XRT-INDUCED).
  • Cell of origin (board phrasing): meningiomas arise from what cells?

    MENINGOTHELIAL / ARACHNOID CAP CELLS.
  • Why can meningiomas occur “anywhere” in brain/spine?

    Arachnoid cap cell rests exist THROUGHOUT THE CNS.
  • WHO meningioma grades?

    GRADE 1 / GRADE 2 / GRADE 3 (typical / atypical / anaplastic).
  • Mitotic cutoff for GRADE 1 meningioma (per notes)?

    < 4 mitoses per high-power field.
  • Mitotic range for GRADE 2?

    4–20 mitoses/HPF.
  • Mitotic cutoff for GRADE 3?

    > 20 mitoses/HPF.
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