Brain evolution

22 important questions on Brain evolution

Give the 3 unifying principles nervous systems have to meet

Uniformity in nerve cell function
Great diversity in nervous systems organization
Function to perceive stimuli and generate a response

Describe the form and function of a neuron (+ axon, synapse)

Smallest cellular unit of nervous system.
Most organelles in cell body: nucleus with genetic material, mitochondria for energy generation + others
Most have dendrites: extensions that receive signals from other neurons
Cone shaped base of axon: axon hillock -> where signals from many incoming neurons are summed up + integrated -> creates new signal transmitted by axon.
Axon: much longer extension transmitting signals to other cells at synapses
Synapse: junction between axon and another cell
Synaptic terminal of 1 axon passes information across synapse in form of chemical messengers: neurotransmitters

Name the 3 categories of functional neurons + describe function

Sensory: transmit information about external stimuli (e.g. Light, touch, smell)
Interneurons: integrate (analyze + interpret) information
Motor neurons: transmit signals to muscle cells -> contract
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Describe the nervous system of Cnidarians (jellyfish, anemones, corals) (nets, synapses, potentials, contraction)

Loosely organized, not centralized nets
Most synapses electrical, not chemical -> action potentials not transmitted by neurotransmitters
Impulses bi-directional, travel through entire nerve net -> stimulation at any point -> whole body contraction

Which cnidarians show centralization and how

Medusa jellyfish -> anatomical and functional clusters of nerve cells -> coordinate more complex motor tasks requiring coordination (e.g. Swimming/feeding)
Swimming: mantle must open and contract in coordinated way to move through water
Feeding: mouth must bend towards tentacles holding the prey

Describe cephalisation (neural tissue, head, bilateral, enlargement, evolution, cord)

Evolutionary tendency to concentrate neural tissue to one end of bilaterally symmetrical animal -> creates head
Bilateral animals: more active, display complex behaviour through concentration of sensory organs + feeding structures at head/forward moving part of body
Occurs with enlargement of anterior ganglia -> enables animal to receive sensory input and control feeding -> evolution of the first brains
Anterior brain: connected to nerve cord -> basic design for all organisms with CNS

Name the 4 times and in which groups in which  encephalisation occured in vertebrate evolution and which group is clearly more advanced cognitively + why

Agnathans (jawless fish),
Cartilaginous fish,
ray-finned fish,   
Tetrapods (phylogenetic group humans belong to)
No group of vertebrates clearly more advanced cognitively than another (overlap of body to brain polygons of fish, birds and mammals)

Which parts of the brain become more predominant than others in vertebrate brain evolution (+ which ones get smaller)

Relative increase in forebrain (telencephalon)
Relative decrease in midbrain (mesencephalon)

From which 3 parts  did the modern vertebrate CNS evolve

Brain blister
Notochord
Dorsal nerve cord
(of lancet fish (amphioxus) and sea squirt (tunicata))

What is the impact of more pressure on nerve cells (sensory receptors e.g.)

More pressure -> high frequency of action potentials per receptors
Gentle pressure -> low frequency

What are the advantages of myelinisation/describe evolution of myelinated axon (4)

Faster transmission of axon potential -> saltatory conduction
Longer and thinner axons, nerves
Body growth possible 
Jump start evolution of intelligence

Why do cold and warm blooded animals have to negotiate their surface to volume ratio

Cold blooded: to take up enough heat and warm up their body
Warm blooded: to not lose too much body heat

Describe the blueprint of vertebrate's brains (+ function, variation)

Forebrain (prosencephalon): processing olfactory input, regulation of sleep, learning, complex processing
Midbrain (metencephalon): routing of sensory input
Hindbrain (rhombencephalon): involuntary activities and motor activities 
Variation between regions in different vertebrates -> reflect relative importance of particular brain function

Name the 4 general (big?) trends of brain evolution during transition from water to land

Relative size of brain increases
Increase compartmentalization of function
Increasing in complexity of forebrain, especially telencephalon
Physical plasticity of brain diminishes

What happened with the 3 brain vesicles (prosen, mesen and rhombencephalon) during ontogenetics development

Became 5 vesicles:
Telencephalon
Diencephalon
Mesencephalon
Metencephalon
Myencephalon

Name the 2 smaller adaptations of the evolution of the brain

Optic vesicles became retina
Sylvius aquaduct appears due to relative increase diencephalon and metencephalon

Name/describe the most prominent development in brain evolution (somatotopic, homunculus, input, output, function) (+ parts it includes (7)  + functions)

Massive increase of telencephalon -> rise of the cortex
Tectum:
Somatotopic organisation
'homonculus'
Input: retinal, auditory, somatosensory
Output: oculomotory, somatomotory, motor-centra
Main function: direct behavioural responses to spatial stimuli
Rhinencephalon:
Olfactory + vomeronasal input
Evolved to limbic system in higher vertebrates
Pallium + subpallium:
evolution from tube to hemispheres
Avian ridge (hyperstriatum):
Song system in singing birds -> similar function to language processing center in humans
Hippocampus          
Olfactory pallium in primitive vertebrates
Memory storage in mammals
Globus pallidum
Eye movements
Motivation
Convolutions (led to increase in relative brain size)
Gyration
Sulcation
Increased surface area

Which structure does the myelencephalon contain + give its functions

Medulla oblongata
Involuntary reflexes
Facial muscles control
Originally: control of gill arches in fish

Which structures does the metencephalon contain + give its functions

Cerebellum: reflex control of skeletal muscles
Pons: connects cerebrum and cerebellum

What is special about the cerebellum of mormyrids (elephant nose fish)  + why is it disadvantageous for ectotherms to have large brains

Takes up 2% of whole body, instead of 0.7% like other fish

Disadvantage: consume 1/13 of energetic costs of endotherms (dont need to heat body) but brain expenditure is simular -> therefore more expensive for ectothermics to have large brain when whole-body energy budget is considered

How do fish brains adapt to prey and habitat (give few examples)

Closer to shore: more visual
Deeper in open waters: more olfactory

Describe the nervous systems of the following invertebrates: platyhelminthes (flatworms), Annelids, insects, spiders, molluscs, cephalopods

Platyhelminthes + Annelids: diffuse, rope ladder like system, ganglia at intersections. Same type ganglia connected by lateral commissures. Ganglia different types connected by connectives
Organised ventrally (instead of dorsally in vertebrates)
Annelids: primitive brain of fused bilaterally organised ganglia connected by commissures, equipped with sensory organs, simplest organism with CNS
MOET UITGEBREID WORDEN

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