How does the immune system distinguish among pathogens? - Where immune cells function and how they travel

3 important questions on How does the immune system distinguish among pathogens? - Where immune cells function and how they travel

Where do immune cells function?

  • Primary and secondary lymphoid organs
  • Sites of infection, inflammation, and surveillance 

How do immune cells travel?

They travel through the blood and lymphatic circulatory systems, guided by specific molecular signals that direct them to sites of disease or infection

What are the routes of immune cells?

  1. General circulation (patrolling)
  2. Homing to lymphoid organs (nodes have cytokines that recruit immune cells)
  3. Recruitment to infection or disease sites (chemotaxis)

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