Vitamins - Water soluble

4 important questions on Vitamins - Water soluble

Which species can synthesize Vitamin B12?

Herbivores can synthesize vitamin B12 with colonic/rumen flora

How is vitamin B12 absorbed?

It requires intrinsic factor from parietal cells to bind to enterocyte receptors in the ileum. It is absorbed via endocytosis

How do vegetarians not have vitamin B12 deficiency?

Enterohepatic recycling of vitamin B12 occurs, which consists of repeated absorption from gut and secretion into bile
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What does low serum vitamin B12 suggest?

1. Exocrine pancreas insufficiency
2. SI bacterial overgrowth and malabsorption
3. Ileal disease or resection

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