Intestinal mucosa - Secretion - Bicarbonate
3 important questions on Intestinal mucosa - Secretion - Bicarbonate
Where does bicarbonate secretion occur?
Small intestine
How does bicarbonate become secreted?
1. Coupled Na+/HCO3- transport
2. Cl-/HCO3- antiporter, resulting in increase of pH in lumen
3. Selective HCO3- channels, resulting in increase of pH in lumen
2. Cl-/HCO3- antiporter, resulting in increase of pH in lumen
3. Selective HCO3- channels, resulting in increase of pH in lumen
How does bicarbonate get reabsorbed back to the cell?
Luminal bicarbonate is broken down into H2O + CO2 and reabsorbed back into the cell. H2O + CO2 become bicarbonate via carbonic anhydrase
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