Cecum and colon - Absorption in cecum and colon
3 important questions on Cecum and colon - Absorption in cecum and colon
What is absorbed in the cecum and colon?
Nutrients (e.g. VFAs from fermentation, vitamins from colonic bacteria), and electrolytes/water (no tight junctions in colon, only active absorption of electrolytes and water)
What mechanism is used in the colon to absorb sodium and chloride?
1. Coupled Na+/Cl- absorption: Cl- and Na+ in, HCO3- and H+ out
2. Chloride-bicarbonate exchange: Cl- in, HCO3- out
If low acid: HCO3 is reabsorbed via Na+/H+ antiporter
2. Chloride-bicarbonate exchange: Cl- in, HCO3- out
If low acid: HCO3 is reabsorbed via Na+/H+ antiporter
How is K+ absorbed in the colon?
Absorption of the majority of water in proximal GI leaves [K+] higher in the colon, leads to passive diffusion of K+
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