Absorption of vitamins and minerals - Copper and Zinc

4 important questions on Absorption of vitamins and minerals - Copper and Zinc

How are copper and zinc absorbed?

Divalent metal carriers: DMT-1 also transports zinc, copper, and cadmium

How are copper and zinc stored in enterocytes?

They are bound to metallothionein in golgi apparatus

What happens with zinc supplementation?

Reduced copper absorption due to competition for DMT-1 carrier
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What happens when copper cannot be transported into bile?

Accumulation of copper in hepatocytes leading to fatal hepatitis (e.g. Bedlington terriers)

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