ENS - Neurotransmitters - Excitatory

3 important questions on ENS - Neurotransmitters - Excitatory

What are the excitatory neurotransmitters of the ENS?

1. Acetylcholine (ACh)
2. Substance P

What is the effect of acetylcholine in ENS?

Smooth muscle contraction, intestinal secretions, release of enteric hormones, blood vessel dilation

What is the effect of Substance P in ENS?

Pain perception, vomiting if in chemoreceptor trigger zone of medulla.

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