Immunodeficiencies - Secondary immunodeficiency

7 important questions on Immunodeficiencies - Secondary immunodeficiency

What is secondary immunodeficiency?

The immune system that is originally healthy becomes damaged

What are the causes of secondary immunodeficiency?

  1. Microorganisms (mostly viruses)
  2. Toxins
  3. Stresses
  4. Aging
  5. Malnutrition

What is Infectious bursal disease virus (IBDV)?

It is the infection of primary lymphoid organs including bursa, spleen and thymus. The bursa never recovers and B cells in infected chicks can no longer develop.
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What is Canine Distemper Virus?

It is the infection of secondary lymphoid organs, initially infecting tonsils and bronchial lymph nodes, then spreads to lymphocytes in blood, other lymph nodes, spleen, MALT, thymus, and bone marrow. Results in loss of T and B cells as well as macrophages

How does malnutrition affect immunodeficiencies?

Malnutrition leads to dendritic cell dysfunction.

How does trauma affect the immune system?

Excessive exercise causes immunosuppression

How does aging affect the immune system?

As host ages, the immune system weakens.

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