Learning Goal - Cluster of Differentiation (CD)
3 important questions on Learning Goal - Cluster of Differentiation (CD)
What are CDs involved in cell adhesion in neutrophils?
- CD11a/CD18 (LFA-1) = binds ICAM-1 on endothelial cells, important for adhesion during mobilization
- CD11b/CD18 (CR3) = adhesion and complement mediated phagocytosis
- CD11c/CD18 = similar role in monocytes and macrophages
What are CDs involved in opsonization in neutrophils?
What are CDs involved in complement receptors?
2. CD35 (CR1) = binds C3b, important for immune complex clearance and phagocytosis
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