Innate Immunity II-2 - Density of cells
4 important questions on Innate Immunity II-2 - Density of cells
What happens to the number of neutrophils during infection?
What are the two types of neutrophils density-wise?
NDNs (normal-density neutrophils): standard, mature segmented neutrophils found in bottom layers)
LDNs (low-density neutrophils): lighter, immature neutrophils from emergency granulopoiesis foudn in top/middle layers
What are the two types of neutrophils function-wise?
N1 (anti-tumor): They are from high-normal density nucleus neutrophils, produce TNF-a and interferons
N2 (pro-tumor): They are from low lobulated nucleus neutrophils, perform NETosis
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How does anti-tumour neutrophil polarization work?
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