B cells and Antibodies - B cells - BCRs and antibodies
10 important questions on B cells and Antibodies - B cells - BCRs and antibodies
What do B cells need to produce a strong antibody response?
2. Stimulation PRRs
3. Cytokines
4. Helper CD4+ T cells
5. Complement
What are the two types of BCRs?
What makes BCRs different from antibodies
2. They bind to specific antigens to activate the B cell
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What makes antibodies different from BCRs?
2. They counteract a specific antigen
3. They bind to specific antigens to elicit immune responses through complement pathway and can recruit other immune cells to destroy pathogens
What are the five types of antibodies?
2. IgM: very large Ig produced during primary immune response
3. IgA: Ig responsible for defense of mucosal surfaces
4. IgE: Ig responsible for immunity to parasitic worms and allergies, found in very small quantities
5. IgD: Ig found on the surface of immature lymphcoytes
Which antibody is stronger at the second exposure of the same antigen?
Which antibody is stronger at the first exposure of the same antigen?
Which immunoglobulin has the longest half life?
Which immunoglobulin has the highest complement-fixing capacity?
Which immunoglobulin has the highest anaphylactic (type I) hypersensitivity?
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