Lymphocytes - Natural killer cells - Surface receptors
4 important questions on Lymphocytes - Natural killer cells - Surface receptors
What are the types of surface receptors on NK cells?
- Inhibitory = DON'T KILL
They are usually balanced, but they will follow the stronger signals
What are examples of activating receptors on NK cells?
- MICA/MICB
- NKp46
- CD16
What are examples of inhibitory receptors on NK cells?
- CD158 (KIR)
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What are Natural Killer T cells?
- They use an invariant T cell receptor to respond to antigens presented by a molecule called CD1d (specialized MHC class I molecule)
- Respond much quicker than conventional T cells
- Activated by glycolipid antigens, as opposed to only peptides
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