Summary: Principles Of Human Genetics
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2 Single-Gene Inheritance
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2.2 Powerpoint
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Name two key functions of meiosis
Two key functions of meiosis are to halve the DNA content and to reshuffle the genetic
content of the organism to generate genetic diversity among the progeny -
3 Independent Assortment of Genes
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3.2 Powerpoint
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Ratio in a dihybrid cross
9:3:3:1 -
4 Genomes and Genomics
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4.2 Powerpoint
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What is comparative genomics?
A field that compares genomes across species to understand evolution, gene function, and genome organization -
What is a homologous gene?
Agene that isshared betweenspecies due tocommon ancestry , though it may havediverged overtime
gen dat bij verschillende soorten voorkomt en van een gemeenschappelijke voorouder afstamt.
bijvoorbeeld het gen voor ogen bij mensen en bij vliegen -
What does comparative genomics reveal?
Variation in homologous genes between humans and other species (e.g., mouse, dog, whale, bird) helping to identify conserved and divergent regions -
Example of synteny in humans and mice?
Human chromosome 17 shows synteny with mouse chromosome 11 - many genes are in the same order, indicating shared ancestry -
Why are mice oftend used in genomic comparisons?
Mice are genetically similar to humans and serve as a model organism due to their short generation time and well-annotated genome -
What can conserved gene sequences suggest?
That a gene is functionally important and has been preserved through evolution -
What can divergent regions between species indicate?
Species-specific traits, adaptations, or changes in gene regulation -
5 Population Genetics
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(p + q)^2 = p^2 + 2pq + q^2 what does p^2 represent
Individual who are homozygous dominant
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