Oogenesis and formation of primordial follicles - regulation of ovarian cyclicity
4 important questions on Oogenesis and formation of primordial follicles - regulation of ovarian cyclicity
The hypothalamic-pituitary axis and there control of the gonadal function?
- In the pituitary gland are most of the reproduction hormones produced.
- hypothalamus is neuroendocrine, behavioural and autonomic functions
- neurons in the hypothalamus communicate with anterior lobe of pituitary utilizing a special circulatory modification = hypothalamo-hypophyseal portal system
- the posterior lobe of the pituitary does not have a portal system. neuro-hormones are deposited directly into capillaries in the posterior lobe of the pituitary
3 types of patterns of hormonal secretion by the reproduction system:
- Episodic
- basal
- sustained
- LH to induce the ovulation
This action depends on 3 things, 1, pattern and duration of secretion, 2, half-life time, 3, receptor density and 4, receptor-hormone affinity.
Ovarian hormons regulate gonadotrophin secretion, which 2 types of feedback?
- a negative feedback, resembling that in males, in which oestrogens, progestagens and inhibin depress gonadotrophin output.
- a positive feedback effect in which an increase, or surge, of LH and FSH secretion is induced principally by oestrogen.
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progestrone regulates FSH and LH secretion negatively in this way.......?
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