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Summary: Samenvatting Trends In Stem Cell Biology

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Read the summary and the most important questions on Samenvatting trends in stem cell biology

  • 1 Embryonic stem cells

    This is a preview. There are 13 more flashcards available for chapter 1
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  • What are the two broad types of stem cells in mammals?

    1. Embryonic stem cells (ESCs) --> which are isolated from the inner cell mass of blastocysts
    2. Adult stem cells
  • What are plutipotent cells (embryonic stem cells)?

    Cells who are capable of differentiation into all three germlayers (ecto-, endo-, and mesoderm)
  • What is multipotency in adult stem cells?

    Progenitor cells (hematopoetic stem cell)
  • What is oligopotency in adult stem cells?

    E.g myeloid stem cell (not lymphoid lineage)
  • What is unipotency in adult stem cells?

    Differentiate into one cell only
  • Explain the term 'waddington's landscape'

    It states that the totipotent cells during development loose potency and become a single cell type. Imagine it as a totipotent ball rolling down from a hill, which is a one-way direction.
  • How do you call it if you go from one mulitopotent to another mulitpotent cell?

    Trans differentiation
  • How do you call it if you go 'uphill' in the waddington's landscape?

    Regeneration
  • What are the 5 different types of pluripotent stem cells?

    1. Embryonic stem cells (ESCs)
    2. Embryonal Carcinoma cells (ECs)
    3. Embryonic Germ Cells (EGCs)
    4. Epiblast stem cells (EpiSCs; primed ES cells)
    5. Induced pluripotent stem cells (iPCSs)
  • What are the characteristics of pluripotency?

    1. They can still form every cell in an organism (ecto-, meso-, endoderm)
    2. self-renewal

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