Skeletal System - Ossification & Growth

6 important questions on Skeletal System - Ossification & Growth

At what age do epiphyseal plates close in most individuals?


Around 18–25 years

What is appositional growth?

Increase in bone thickness/diameter

What hormone is critical for bone growth during childhood?

Growth Hormone
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Which hormones are important for bone maintenance in adults?

Sex hormones (estrogen & testosterone)

Q: What are the steps of intramembranous ossification?

  • 1. Mesenchymal cells cluster → osteoblasts
  • 2. Osteoblasts secrete osteoid → trapped → osteocytes
  • 3. Formation of spongy bone + periosteum
  • 4. Formation of compact bone
  • What are the steps of endochondral ossification?

    A:
    1. Cartilage model develops
    2. Calcification & cavitation
    3. Primary ossification center forms (diaphysis)
    4. Secondary ossification centers form (epiphyses)
    5. Growth plates remain until adulthood

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