Sleep and geriatrics

41 important questions on Sleep and geriatrics

What are the main changes in human sleep characteristics that occur with ageing?

  • The circadian system and sleep regulation become less robust.
  • Changes include:
1. Phase advance tendency
  1. Decreased total sleep time (TST)
  2. Decreased sleep efficiency
  3. Increased sleep fragmentation

How does ageing impact sleep electro-physiology?

- Ageing leads to:
  1. Decreased slow-wave activity indicating shallower sleep
  2. Reduced density of fast spindles during non-rapid eye movement sleep
  3. Changes affecting synaptic plasticity and memory consolidation

What limitations are associated with self-reported sleep quality in the elderly?

- Self-reported quality is often biased due to:
  1. Polymorbidity complicating data reliability
  2. Expectation discrepancies between age groups
  3. Tools like PSQI relying on subjective input
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How do total sleep time and sleep efficiency change with age?

- Total sleep time (TST) decreases with age:
  1. Roughly 10 minutes per decade decrease
  2. Sleep efficiency declines similarly
  3. Wake after sleep onset (WASO) more than doubles post-65

What neurophysiological pathways are linked to age-related sleep changes?

- Changes involve:
  1. Decreased amplitude and density of slow waves
  2. More frequent periodic limb movements during sleep
  3. Cyclic alternating patterns leading to fragmented sleep

In what ways does sleep quality relate to cognitive health in older adults?

- There is a two-way relationship:
  1. Changes in sleep quality can indicate neurodegenerative diseases
  2. Sleep variations can precede cognitive impairment
  3. Sleep disturbances affect brain health

How does daytime sleep affect older adults?

- Daytime sleep can have:
  1. Favourable effects by improving total sleep
  2. Negative effects when excessive
  3. Implications for overall sleep quality through flexibility post-retirement

What are the main characteristics of human sleep changes with ageing?

Changes in sleep include:
  • Blunted circadian system
  • Decreased total sleep time
  • Decreased sleep efficiency
  • Increased sleep fragmentation

How does sleep architecture evolve with aging?

Aging affects sleep architecture by:
  1. Tendency to phase advance
  2. Decreased total sleep time
  3. Reduced sleep efficiency
  4. Increased sleep fragmentation

What electrophysiological changes occur in sleep with age?

Ageing causes:
  • Decreased slow-wave activity
  • Reduced density of fast spindles
  • Fewer K-complexes during non-rapid eye movement sleep
  • Potential impacts on synaptic plasticity

How do men and women differ in their sleep patterns?

Key differences include:
  • Distinct hormonal signalling
  • Men's and women's sleep architectures vary
  • Women generally have a longer sleep onset latency
  • Variations in total sleep time between genders

How does sleep quality relate to cognitive health in the elderly?

There's a two-way relationship where:
  • Poor sleep quality may lead to cognitive impairment
  • Subtle sleep variations can indicate neurodegenerative diseases
  • Sleep alterations often go unnoticed without complaints

Why might older adults complain less about sleep quality compared to younger adults?

Factors include:
  • Tolerance to gradual sleep changes
  • Lower expectations for sleep quality
  • Increased flexibility for daytime naps after retirement
  • Lack of complaints despite objective disturbances

What are some limitations of subjective sleep complaints in older adults?

Limitations include:
  1. Reliance on self-report data
  2. Challenges from polymorbidity
  3. Potential bias in assessment tools like PSQI
  4. Difficulty separating sleep issues from health problems

What are the expected changes in total sleep time (TST) with age?

TST typically decreases with aging due to:
  • An expected decrease of about 10 minutes per decade
  • Minimal changes between ages of 60 and 80
  • Uncertainty in over 80 years due to data scarcity

How does sleep efficiency change with age?

Sleep efficiency decreases as people age, resulting in:
  • Lower percentage of time asleep while in bed
  • Similar decline to total sleep time
  • Increased feelings of tiredness due to less effective sleep

What influences wake after sleep onset (WASO) in the elderly?

WASO increases due to:
  • More fragmented sleep in older adults
  • Doubles for those >65 compared to early adulthood
  • Reflects difficulties in maintaining sleep

What happens to the arousal index with ageing?

The arousal index shows:
  • Increased interruptions of sleep
  • Direct association with fragmentation
  • Affects the quality of rest

How do daytime naps impact sleep quality in older adults?

Daytime naps can:
  • Improve total sleep amount over 24 hours
  • Provide benefits, but can have negative effects in certain scenarios
  • Help mitigate sleep deprivation issues

What are the common diagnostic issues associated with sleep disorders in the elderly?

A thorough medical history is essential, covering:
  • Medical factors
  • Pharmacological factors
  • Mental health issues
  • Social factors
  • Chronicity and duration of symptoms
  • Daytime sleepiness
  • Sleep patterns

What are some common somatic comorbidities leading to sleep disorders in the elderly?

Key somatic comorbidities include:
  1. Chronic obstructive airway disease
  2. Diabetes mellitus
  3. Renal failure
  4. Hypertension
  5. Arthritis
  6. Stroke
  7. Visual impairment

How does sleep disordered breathing (SDB) prevalence change with age?

The prevalence varies significantly:
  • Estimated between 20% and 63%
  • Factors affecting prevalence include:
1. Sample size
  1. Examination methods
  2. Scoring criteria

What are common symptoms associated with obstructive sleep apnea syndrome (OSAS) in the elderly?

Symptoms include:
  • Intermittent nocturnal hypoxia
  • Sleep fragmentation
  • Excessive daytime sleepiness
  • Associated risks include:
1. Stroke
  1. Mortality
  2. Cognitive impairment

What are key management strategies for restless legs syndrome (RLS) in older individuals?

Management strategies focus on:
  1. Lifestyle modifications (e.g., avoiding alcohol)
  2. Reducing iatrogenic factors
  3. Maintaining high-normal peripheral iron stores
  4. Pharmacotherapy tailored for age-related risks

How is sleep latency and sleep architecture affected in dementia patients?

Common changes include:
  • Prolonged sleep latency
  • Decreased slow-wave sleep
  • Increased daytime sleep episodes
  • Frequent night-time awakenings
  • Worsening neuropsychiatric symptoms such as agitation

What role does melatonin play in sleep disorders among the elderly?

Melatonin's role includes:
  • May have neuroprotective effects
  • Decreases with age
  • Particularly low in Alzheimer’s patients
  • Affected by neurodegenerative changes

What factors increase the risk of cognitive impairment related to sleep disorders?

Risk factors include:
  1. Mid- and late-life insomnia
  2. Daytime sleepiness
  3. Long sleep duration
  4. Night-time sleep disruption
  5. Cardiovascular disease history

What are the consequences of irregular sleep-wake rhythm disorder (ISWRD) in dementia patients?

Consequences include:
  • Rapid cognitive deterioration
  • Increased hospitalization rates
  • Higher home placement rates
  • Symptoms such as anxiety and agitation
  • 50% of dementia cases may develop ISWRD

What factors contribute to sleep disorders in the elderly?

Consideration must include:
  • Somatic comorbidities (like diabetes, arthritis)
  • Polypharmacy (medication side effects)
  • Mental factors (such as anxiety, depression)
  • Social dimensions (loneliness, care activities)

What symptoms indicate the presence of sleep-disordered breathing (SDB) in the elderly?

Prominent symptoms include:
  1. Daytime sleepiness
  2. Irregular breathing during sleep
  3. Apnea-hypopnea index
  4. Cognitive impairment

How is RLS (Restless Legs Syndrome) characterized in older adults?

Key characteristics are:
  • Significant discomfort in legs, occurring at least twice a week
  • Increased risk of falls due to nocturnal wandering
  • Periodic limb movement disorder is commonly associated

What treatments are suggested for insomnia in elderly patients?

Insomnia treatment should include:
  1. Pharmacological interventions
  2. Non-pharmacological interventions
  3. Consideration for underlying pathology
  4. Chronotherapy

What sleep characteristics change with age?

Common age-related changes are:
  • Increased sleep latency
  • Reduced total sleep time
  • Reduced sleep efficiency
  • Frequent nocturnal awakenings

What role does polysomnography play in diagnosing sleep disorders in the elderly?

Polysomnography helps by:
  • Providing objective quantification of sleep problems
  • Supporting psychoeducation for patients
  • Assisting in identifying nocturnal hypoxia

How does obstructive sleep apnea (OSA) impact elderly individuals?

OSA can lead to:
  1. Intermittent nocturnal hypoxia
  2. Sleep fragmentation
  3. Increased risks for:
  • Stroke
  • - Cardiac failure
  • - Cognitive impairment

What is the relationship between sleep disorders and dementia?

The relationship is:
  • Bidirectional
  • Increased risk of dementia from disrupted sleep
  • Sleep disorders can worsen cognitive decline

Which patient behaviors should be observed for RLS in elderly patients?

Observed behaviors include:
  • Rubbing or groaning
  • Excessive motor activity (kicking, pacing)
  • Inability to verbalize symptoms

What lifestyle modifications can help manage RLS in older adults?

Recommended modifications are:
  • Avoidance of alcohol
  • Moderate physical exercise
  • Reducing iatrogenic factors (stimulants)

What are some common comorbid conditions related to sleep problems in the elderly?

Common comorbid conditions include:
  • Chronic obstructive airway disease
  • Cardiovascular diseases
  • Diabetes mellitus
  • Arthritis

What implications does sleep disturbance have for caregivers of elderly individuals?

Implications can include:
  • Increased caregiver burden
  • Higher rates of hospital admissions
  • Greater need for residential care

How does melatonin affect elderly patients with sleep disorders?

Melatonin effects are:
  • Decreases with age
  • Low levels associated with Alzheimer’s dementia
  • Potential neuroprotective effects highlighted

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