Sleep and geriatrics
41 important questions on Sleep and geriatrics
What are the main changes in human sleep characteristics that occur with ageing?
- The circadian system and sleep regulation become less robust.
- Changes include:
- Decreased total sleep time (TST)
- Decreased sleep efficiency
- Increased sleep fragmentation
How does ageing impact sleep electro-physiology?
- Decreased slow-wave activity indicating shallower sleep
- Reduced density of fast spindles during non-rapid eye movement sleep
- Changes affecting synaptic plasticity and memory consolidation
What limitations are associated with self-reported sleep quality in the elderly?
- Polymorbidity complicating data reliability
- Expectation discrepancies between age groups
- Tools like PSQI relying on subjective input
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How do total sleep time and sleep efficiency change with age?
- Roughly 10 minutes per decade decrease
- Sleep efficiency declines similarly
- Wake after sleep onset (WASO) more than doubles post-65
What neurophysiological pathways are linked to age-related sleep changes?
- Decreased amplitude and density of slow waves
- More frequent periodic limb movements during sleep
- Cyclic alternating patterns leading to fragmented sleep
In what ways does sleep quality relate to cognitive health in older adults?
- Changes in sleep quality can indicate neurodegenerative diseases
- Sleep variations can precede cognitive impairment
- Sleep disturbances affect brain health
How does daytime sleep affect older adults?
- Favourable effects by improving total sleep
- Negative effects when excessive
- Implications for overall sleep quality through flexibility post-retirement
What are the main characteristics of human sleep changes with ageing?
- Blunted circadian system
- Decreased total sleep time
- Decreased sleep efficiency
- Increased sleep fragmentation
How does sleep architecture evolve with aging?
- Tendency to phase advance
- Decreased total sleep time
- Reduced sleep efficiency
- Increased sleep fragmentation
What electrophysiological changes occur in sleep with age?
- Decreased slow-wave activity
- Reduced density of fast spindles
- Fewer K-complexes during non-rapid eye movement sleep
- Potential impacts on synaptic plasticity
How do men and women differ in their sleep patterns?
- Distinct hormonal signalling
- Men's and women's sleep architectures vary
- Women generally have a longer sleep onset latency
- Variations in total sleep time between genders
How does sleep quality relate to cognitive health in the elderly?
- Poor sleep quality may lead to cognitive impairment
- Subtle sleep variations can indicate neurodegenerative diseases
- Sleep alterations often go unnoticed without complaints
Why might older adults complain less about sleep quality compared to younger adults?
- Tolerance to gradual sleep changes
- Lower expectations for sleep quality
- Increased flexibility for daytime naps after retirement
- Lack of complaints despite objective disturbances
What are some limitations of subjective sleep complaints in older adults?
- Reliance on self-report data
- Challenges from polymorbidity
- Potential bias in assessment tools like PSQI
- Difficulty separating sleep issues from health problems
What are the expected changes in total sleep time (TST) with age?
- An expected decrease of about 10 minutes per decade
- Minimal changes between ages of 60 and 80
- Uncertainty in over 80 years due to data scarcity
How does sleep efficiency change with age?
- Lower percentage of time asleep while in bed
- Similar decline to total sleep time
- Increased feelings of tiredness due to less effective sleep
What influences wake after sleep onset (WASO) in the elderly?
- More fragmented sleep in older adults
- Doubles for those >65 compared to early adulthood
- Reflects difficulties in maintaining sleep
What happens to the arousal index with ageing?
- Increased interruptions of sleep
- Direct association with fragmentation
- Affects the quality of rest
How do daytime naps impact sleep quality in older adults?
- Improve total sleep amount over 24 hours
- Provide benefits, but can have negative effects in certain scenarios
- Help mitigate sleep deprivation issues
What are the common diagnostic issues associated with sleep disorders in the elderly?
- Medical factors
- Pharmacological factors
- Mental health issues
- Social factors
- Chronicity and duration of symptoms
- Daytime sleepiness
- Sleep patterns
What are some common somatic comorbidities leading to sleep disorders in the elderly?
- Chronic obstructive airway disease
- Diabetes mellitus
- Renal failure
- Hypertension
- Arthritis
- Stroke
- Visual impairment
How does sleep disordered breathing (SDB) prevalence change with age?
- Estimated between 20% and 63%
- Factors affecting prevalence include:
- Examination methods
- Scoring criteria
What are common symptoms associated with obstructive sleep apnea syndrome (OSAS) in the elderly?
- Intermittent nocturnal hypoxia
- Sleep fragmentation
- Excessive daytime sleepiness
- Associated risks include:
- Mortality
- Cognitive impairment
What are key management strategies for restless legs syndrome (RLS) in older individuals?
- Lifestyle modifications (e.g., avoiding alcohol)
- Reducing iatrogenic factors
- Maintaining high-normal peripheral iron stores
- Pharmacotherapy tailored for age-related risks
How is sleep latency and sleep architecture affected in dementia patients?
- Prolonged sleep latency
- Decreased slow-wave sleep
- Increased daytime sleep episodes
- Frequent night-time awakenings
- Worsening neuropsychiatric symptoms such as agitation
What role does melatonin play in sleep disorders among the elderly?
- May have neuroprotective effects
- Decreases with age
- Particularly low in Alzheimer’s patients
- Affected by neurodegenerative changes
What factors increase the risk of cognitive impairment related to sleep disorders?
- Mid- and late-life insomnia
- Daytime sleepiness
- Long sleep duration
- Night-time sleep disruption
- Cardiovascular disease history
What are the consequences of irregular sleep-wake rhythm disorder (ISWRD) in dementia patients?
- Rapid cognitive deterioration
- Increased hospitalization rates
- Higher home placement rates
- Symptoms such as anxiety and agitation
- 50% of dementia cases may develop ISWRD
What factors contribute to sleep disorders in the elderly?
- Somatic comorbidities (like diabetes, arthritis)
- Polypharmacy (medication side effects)
- Mental factors (such as anxiety, depression)
- Social dimensions (loneliness, care activities)
What symptoms indicate the presence of sleep-disordered breathing (SDB) in the elderly?
- Daytime sleepiness
- Irregular breathing during sleep
- Apnea-hypopnea index
- Cognitive impairment
How is RLS (Restless Legs Syndrome) characterized in older adults?
- Significant discomfort in legs, occurring at least twice a week
- Increased risk of falls due to nocturnal wandering
- Periodic limb movement disorder is commonly associated
What treatments are suggested for insomnia in elderly patients?
- Pharmacological interventions
- Non-pharmacological interventions
- Consideration for underlying pathology
- Chronotherapy
What sleep characteristics change with age?
- Increased sleep latency
- Reduced total sleep time
- Reduced sleep efficiency
- Frequent nocturnal awakenings
What role does polysomnography play in diagnosing sleep disorders in the elderly?
- Providing objective quantification of sleep problems
- Supporting psychoeducation for patients
- Assisting in identifying nocturnal hypoxia
How does obstructive sleep apnea (OSA) impact elderly individuals?
- Intermittent nocturnal hypoxia
- Sleep fragmentation
- Increased risks for:
- Stroke
- - Cardiac failure
- - Cognitive impairment
What is the relationship between sleep disorders and dementia?
- Bidirectional
- Increased risk of dementia from disrupted sleep
- Sleep disorders can worsen cognitive decline
Which patient behaviors should be observed for RLS in elderly patients?
- Rubbing or groaning
- Excessive motor activity (kicking, pacing)
- Inability to verbalize symptoms
What lifestyle modifications can help manage RLS in older adults?
- Avoidance of alcohol
- Moderate physical exercise
- Reducing iatrogenic factors (stimulants)
What are some common comorbid conditions related to sleep problems in the elderly?
- Chronic obstructive airway disease
- Cardiovascular diseases
- Diabetes mellitus
- Arthritis
What implications does sleep disturbance have for caregivers of elderly individuals?
- Increased caregiver burden
- Higher rates of hospital admissions
- Greater need for residential care
How does melatonin affect elderly patients with sleep disorders?
- Decreases with age
- Low levels associated with Alzheimer’s dementia
- Potential neuroprotective effects highlighted
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