Tutorial title - Hepatobiliary System - Cholelithiasis
5 important questions on Tutorial title - Hepatobiliary System - Cholelithiasis
What are the risk factors for cholelithiasis (gallstones)?
- Female
- Fertile
- Forty
- Fat
- Fair
- Rapid weight loss leading to more cholesterol than bile acids.
Describe the types of stones associated with cholelithiasis.
- Cholesterol stones: Predominant with dyslipidemia, affluent communities, and >50% crystalline cholesterol monohydrate.
- Pigmented stones: Common in low socioeconomic groups, contain calcium salts, bilirubin, black or brown pigment.
- Mixed stones: Combination of cholesterol, bilirubin, calcium, and phosphate.
What are the clinical features of biliary colic in gallstone disease?
- RUQ pain radiating to the back
- Pain triggered by a fatty meal
- Associated with nausea and vomiting
- Pain is colic in nature, occurring in a palpable or wave manner.
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What complications can arise from gallstones?
- Perforation leading to biliary peritonitis
- Change of colic pain to constant pain
- Absent bowel sounds
- Multi-organ dysfunction (Chypotension)
- CXR may show features of biliary perforation.
What factors contribute to the formation of gallstones?
- Supersaturation of bile fluid with cholesterol
- Decreased bile acid
- Reduced motility
- 80% of gallstone diseases are clinically silent
- Stones can block ducts or cause pain.
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