Pharmacogenomics
34 important questions on Pharmacogenomics
What genetic factors are involved in individual variability in drug response?
What environmental factors are involved in individual variability in drug response?
How can genetic variants be caused?
- Higher grades + faster learning
- Never study anything twice
- 100% sure, 100% understanding
What are Single nucleotide polymorphisms (SNPs)?
What Are Single Nucleotide Variants (SNVs)?
What is the difference between a SNP and a SNV?
What is a Copy Number Variation (CNV)?
How does pharmacogenetics look for genes associated with drug response?
How can we predict the drug response in a individual?
Of which two phases does pharmacokinetics consist?
What does the functionalization phase of pharmacokinetics do?
What does the conjugation reaction phase of pharmacokinetics do?
Why are medicines hydrophilic?
What is cytochrome P450 2D6?
Where is CYP2D6 primarily expressed?
How does CYP2D6 hydroxylate drugs?
By what gene is Cytochrome P450 2D6 encoded?
How can metabolizer phenotypes be predicted?
What is increased enzyme activity most often due to?
What can SNPs in CYP2D6 cause?
How do thiopurines work?
What kind of adverse events can be caused by thiopurines?
For which diseases can thiopurines be used?
How can a thiopurine treatment be done?
How can a thiopurine treatment be monitored?
How can optimization of the thiopurine treatment be done?
What is Thiopurine methyltransferase (TPMT)?
What is Inflammatory bowel disease (IBD)?
What are examples of inflammatory bowel diseases?
What is a side effect of Ribavirin?
How is the anemia with Ribavirin caused?
What is Dihydropyrimidine dehydrogenase deficiency (DPYD)?
What is the function of dihydropyrimidine dehydrogenase?
How can pharmacogenetics be used in the daily practice?
The question on the page originate from the summary of the following study material:
- A unique study and practice tool
- Never study anything twice again
- Get the grades you hope for
- 100% sure, 100% understanding

















