PET - PET in oncology

5 important questions on PET - PET in oncology

What is the difference between spect and pet?

With PET (fluorine 18) two gamma rays are released. With spect only one (out of technetium). In SPECT the detector circles around the patient.

What is the receptor for 18F FDG?

Glucose => more in tumors

What is the advantage of a total body PET scan?

  • Higher sensitivity => you need less of the tracer. Lower the dose => good for pregnant patients.
  • Scan time can be shorter
  • It has more detectors
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Give a very clinical example of why 18F FDG is important.

For patients with lymphoma (lymphatic cancer). It can help with setting up a treatment plan. Initial treatment is based on the stage => you need PET for this already. (chemo or not has high impact on the patient)
- Uptake higher than the liver.

What is the target of fapi?

Fibroblasten of tumorcells.
Fibroblast-activation-protein inhibitors (FAPIs)

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