Healing of epithelial + connective tissues

4 important questions on Healing of epithelial + connective tissues

How do epithelial + connective tissues heal?

Abrasion: partial loss of epidermis of epithelium
- we have mitotically active epithelium, good CT framework, adequate vascular supply

Incision of epidermis, basement membrane, and even dermis:
- we no longer have an intact CT framework, it needs a basement membrane to cross

Epithelial repair: Timeline and requirements

- For JUST epithelium from abrasion: 24-48 hours
- Requires (and usually has): mitotically active epithelium, intact CT network, adequate vascular supply

Epithelial + CT repair: timeline and requirements

For both epithelial + CT from incision: 4-5 days
- Requires (and usually missing one or two): mitotically active epithelium, intact CT network, adequate vascular supply
- Usually missing intact CT network, which requires fibrin
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1st and 2nd intention wound healing

Second intention healing involves open, larger wounds with tissue loss, requires granulation tissue

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