Dysregulation of proliferative cells - Physiology induced

4 important questions on Dysregulation of proliferative cells - Physiology induced

Give an example of physiology induced hypertrophy

Renal disease can lead to systemic hypertension, which leads to myocardial overwork and myocardial hypertrophy as a consequence

Give an example of genetic predisposition leading to hypertrophy

Friesian horses are predisposed to caudal esophageal muscular hypertrophy, causing difficulty swallowing and aspiration of food material

Give an example of physiologic demand based atrophy

Muscle wasting (atrophy) due to lack of nerve input in Rottweilers
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Give an example of pressure induced and ischemic atrophy

Colonic impaction in horses leads to atrophy through chronic obstruction that causes pressure necrosis (tissue death) and functional impairment (loss of muscular strength) of the intestinal wall

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