Summary: Pathology Term Test 4

Read the summary and the most important questions on Pathology Term Test 4

• 1 Inflammation and Repair III

• 1.1 Neutrophilic inflammation

• What is neutrophilic inflammation?

  Also known as acute inflammation, neutrophilic inflammation is a response where neutrophils are the first and main actors to arrive and act in an immune mediated defense mechanism.

• What are some other words to describe neutrophilic inflammation?

  Purulent, suppurative, abscess

• What is the purpose of neutrophils in inflammation?

  Containment/elimination of infection, impaired organ function, and/or injury to host tissue, as well as stimulation of fibrosis

• 1.1.1 Causes

• What are causes of neutrophilic inflammation?

  1. Trauma
     
  2. Foreign material
  3. Thrombosis
  4. Burns
  5. Necrosis
  6. Immune complexes (e.g. Viruses, bacteria)

• 1.1.2 Timing

  This is a preview. There are 2 more flashcards available for chapter 1.1.2
  Show more cards here

• How long do neutrophils take to enter tissues?

  Hours

• 1.1.3 Outcome

• What are the outcomes of neutrophilic/suppurative inflammation?

  1. Resolution: tissue will return to normal and plasmin will take down fibrin
     
  2. Chronic suppurative inflammation
  3. Stimulation of fibrosis
  4. Containment: Abscess formation

• What happens in containment of neutrophils?

  There is continuous neutrophil recruitment and white fibrous capsule formation

• What happens when there is neutrophilic inflammation in the lungs?

  There is pus formation within the alveoli, which is different from large abscesses

• 1.1.4 Pathogenesis

• What is the local tissue response to neutrophilic inflammation?

  Hyperemia (reddening), this is due to vasodilation and increased blood flow to the region

• What is the systemic response to neutrophilic inflammation?

  Systemic arterial hypotension, this is due to vasodilation and decreased pressure of the blood running through vessels