Regulation of cell number and size - Growth factors and cytokines
5 important questions on Regulation of cell number and size - Growth factors and cytokines
What is the mechanism behind cell proliferation/differentiation?
2. Transcription factors produce response elements
3. Gene expression with response elements lead to protein synthesis and cellular responses
Give an example of a paracrine signaling molecule and its receptor & transcription factor
Give an example of an endocrine signaling molecule and its receptor & transcription factor
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What is an example of an endocrine growth factor?
How does HIF-1a get activated?
Basically: O2 = teacher, hydroxyprolines = student in detention, HIF-1a = homework that needs to get done
- If O2 is not present, hydroxyprolines are not bound to them, so they can't degrade HIF-1a
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