Summary: Pharm 1
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Read the summary and the most important questions on Pharm 1
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1 Unit 1
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1.1 Anticoagulants
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What triggers collagen release in the mechanism of action of coagulation modifiers?
Injury or insult to vessel walls triggers collagen release. -
What is the role of platelets in coagulation?
Platelets contribute to platelet aggregation. -
What leads to clot or plug formation?
Platelet aggregation leads to clot or plug formation. -
What is the sequence from prothrombin to fibrin?
Prothrombin is converted to thrombin, which then converts fibrinogen to fibrin. -
What role does Vitamin K play in coagulation?
Vitamin K is involved in coagulation activation. -
What happens after tissue thromboplastin release?
Tissue thromboplastin release leads to coagulation activation. -
1.1.1 Heparins
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What are the contraindications for Heparins?
- Uncontrolled or Active bleeding
- GI ulcerations
- Severe hypertension
- Severe Thrombocytopenia
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What is the form of Enoxaparin (Lovenox)?
Form: Sub-Q only- Prefilled syringes
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What is the antidote for Heparins?
Antidote: Protamine Sulfate -
What is Heparin Induced Thrombocytopenia (HIT)?
Heparin Induced Thrombocytopenia (HIT) can develop days after starting heparin. It can lead to serious conditions such as PE, a stroke, or a heart attack. Symptoms include:- Skin changes
- Pain/swelling
- Breathing difficulties
- Abdominal pain
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Topics related to Summary: Pharm 1
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Lecture title - Anticoagulants - Heparins
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Lecture title - Anticoagulants - Vitamin K antagonisis
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Lecture title - Anticoagulants - Direct thrombin Inhibitors
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Lecture title - Anticoagulants - Direct Factor Xa Inhibitors
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Lecture title - Anticoagulants - Antiplatelet
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Lecture title - Anticoagulants - Thrombolytic Drugs
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Lecture title - Dyslipidemia - HMG-COA reductase Inhibitors
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Tutorial title - HF & Diuretics - Aldosterone Antagonists
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Tutorial title - HF & Diuretics - Angiotensin Receptor Blockers
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Tutorial title - HF & Diuretics - ACE Inhibitors
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Tutorial title - HTN - Calcium Channel Blockers
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Tutorial title - HTN - Direct Renin Inhibitors
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Tutorial title - HTN - Antiadrenergic
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Tutorial title - Angina/ CAD - Organic nitrates
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