Surviving in a Microbial World - Bacterial pathogenesis
3 important questions on Surviving in a Microbial World - Bacterial pathogenesis
What are the steps of bacterial pathogenesis
- Bacterial exposure: source of disease
- Colonization: passing barriers and infecting organism
- Immune evasion: resisting immune response and proliferation
- Infection
How do bacteria evade the immune system?
Virulence factors: Bacteria produce toxins, enzymes, and other factors to directly damage host cells and/or modify the immune synapse.
How do bacteria affect their microenvironment?
Metabolic tuning: Bacteria can create tolerance, limit clearance, and promote their own survival, influencing disease outcomes.
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