Bacterial pathogenesis - Methods of Bacterial pathogenesis management - Barriers, innate, and adaptive immunity
4 important questions on Bacterial pathogenesis - Methods of Bacterial pathogenesis management - Barriers, innate, and adaptive immunity
How do physical barriers react with bacteria?
How does the innate immunity react to bacteria?
Inflammation: Triggers the release of cytokines that attract neutrophils and cause vasodilation, leading to swelling and recruitment
Phagocytosis and NETs: Neutrophils engulf bacteria through phagocytosis or form NETs made of DNAs to trap bacteria
How does the adaptive immunity react to bacteria?
Cellular & humoral immunity: CD4+ cells, CD8+ cells and B cells work together to produce a specific and targeted immune response
Memory: Memory B and T cells are generated to enable faster responses in the future encounters
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How do neutrophils fight back against bacteria
2. Degranulation: release of compounds that are toxic to bacteria to kill them
3. NETosis: forming a net from DNA, trap the bacteria and cannot move anywhere else - acting like glue
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