Calcium - Distribution of Clacium

3 important questions on Calcium - Distribution of Clacium

How much calcium is in the human body?

In a 70kg human, there are ~1.2kg of Ca2+

Where are the major sites for calcium regulation?

Small intestine, 1/3 of calcium absorbed here through hormones

What other organs regulate calcium concentration?

Bone: osteoblasts and osteoclasts
Kidney: Ca2+ absorption in glomerular filtrate as needed
Gut: active and passive Ca2+ absorption, bile/fecal excretion
Muscle cells and others: Ca2+ uptake for functions
Blood plasma: free and bound Ca2+

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