Learning Goal - textbook C - CD8+ Cytotoxic T cells
4 important questions on Learning Goal - textbook C - CD8+ Cytotoxic T cells
How do CD8+ Cytotoxic T cell aid in immune responses?
How are CD8+ T cells activated?
- Endogenous antigens are broken down into peptides and fit into MHC class I
Signal 2: Co-stimulators (CD28 and CD80/86)
Signal 3 (not always required): Cytokines such as IL-12 driving proliferation/differentiation of T cells
How does CD8+ CTLs kill with perforins and granzymes?
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How does CD8+ CTL kill with Fas/FasL pathway?
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