The Inheritance of Complex traits - Powerpoint

8 important questions on The Inheritance of Complex traits - Powerpoint

What are complex traits?

Traits influenced by multiple genes and environmental factors (e.g. Height, blood pressure, diabetes)

What is a quantatitative trait?

A trait that can be measured and show continuous variation, like weight or intelligent

What are polygenic traits?

Traits influenced by many genes (e.g. Skin color, intelligence)
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What is genetic predisposition?

A genetic tendency to develop a certain condition, which may or may not be triggered by the environment

What is GxE interaction?

Gene x Environment interaction - the effect of a gene depends on the environment it's expressed in

What is the liability threshold model?

A model suggesting that a complex diseases occurs when a combined genetic and environmental burden exceeds a threshold

How are complex traits studied?

Using family studies, twin studies, and Genome-Wide Association Studies (GWAS)

Is h2/H2 about selectability or repeatability?

H2 repeatablilty of the genetic performance in same environment
h2 selectability breeders equation

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