Genomes and Genomics - Powerpoint

7 important questions on Genomes and Genomics - Powerpoint

What is comparative genomics?

A field that compares genomes across species to understand evolution, gene function, and genome organization

What is a homologous gene?

A gene that is shared between species due to common ancestry, though it may have diverged over time


gen dat bij verschillende soorten voorkomt en van een gemeenschappelijke voorouder afstamt.   
bijvoorbeeld het gen voor ogen bij mensen en bij vliegen

What does comparative genomics reveal?

Variation in homologous genes between humans and other species (e.g., mouse, dog, whale, bird) helping to identify conserved and divergent regions
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Example of synteny in humans and mice?

Human chromosome 17 shows synteny with mouse chromosome 11 - many genes are in the same order, indicating shared ancestry

Why are mice oftend used in genomic comparisons?

Mice are genetically similar to humans and serve as a model organism due to their short generation time and well-annotated genome

What can conserved gene sequences suggest?

That a gene is functionally important and has been preserved through evolution

What can divergent regions between species indicate?

Species-specific traits, adaptations, or changes in gene regulation

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