How we study the brain - brain/neuroscience
5 important questions on How we study the brain - brain/neuroscience
How many receptors can neurotransmitters interact with? And what do they ultimately do to the neuron?
Why are neurotransmitters stored in vesicles and released upon activation?
They are stored in Vesicles because if they weren't they would be degraded by the molecules around and wouldn’t be able to send a signal.
Having them in vesicles also means there is more control over concentration and stability.
Would this be a direct or indirect agonist or antagonist? SSRIs, selective serotonin reuptake inhibitors. Block the reuptake for serotonin, so once serotonin is released it is not cleared away as fast and lingers longer in the synapse.
Does reduce serotonin, actually increases its presence so is therefore an agonist.
Don’t add any serotonin in so are indirect
(Indirect agonist)
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Would this be a direct or indirect agonist or antagonist? Curare, the arrow poison, blocks acetylcholine receptors at the junction between nerve and muscle. The message arrives in the gap, but the lock is blocked and will not turn, so the muscle is never told to contract including muscles you breath with.
Block receptors meaning they neuron never gets the message (direct)
Decreases transmission (antagonist)
Direct antagonist.
What is the sequence of events for an action potential to be generated and move down the axon?
Inputs are summed up if they reach the threshold then NA+ gates/channels open and NA+ flows in due to diffusion, the inside becomes slightly more positive.
The K+ gates/channels open and K+ flows out due to diffusion.
The inside becomes less positive.
The sodium-potassium pump then then restores NA+ and K+ to their original sides, the pump uses energy because it has to push NA+ and K+ against their natural concentration gradient.
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