Innate Immunity: the induced response to infection
6 important questions on Innate Immunity: the induced response to infection
Wat is een PRR?
PAMP?
DAMP?
Pathogen-associated molecular pattern = het specifieke microb dat kan worden herkent
Damage-associated molecular pattern
Wat is een (phago)lysosoom?
Wat zijn Toll-like receptors?
- Are present in especially macrophages, dendritic cells, and neutrophils
- geven signalen aan macrophagen en dendritische cellen --> belangrijk voor de inschakeling van het adaptive immunesystem
- Twee soorten: 1 de receptoren zitten op de membranen 2 de receptoren zitten op membraan vesicles (herkennen nucleineacids)
- Kunnen de vier soorten micoorganismen herkennen
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Welke cytokinen en welke chemokinen worden gemaakt na activatie van de macrophaag door IL-1B (ook gemaakt door de macrophaag?
IL-6
CXCL8
CCL2
IL-12
Wat is het verschil tussen cytokinen en chemokinen?
Cytokinen: change behavior of neighbouring cells. Binden aan specifieke receptoren. (activation)
Chemokinen: guiding leukocyten to site where they are needed (migration)
Waar zijn neutrofielen opgeslagen? Als ze worden 'opgeroepen' door macrophagen?
En worden ook weer gephagocyteerd door macrophagen.
The question on the page originate from the summary of the following study material:
- A unique study and practice tool
- Never study anything twice again
- Get the grades you hope for
- 100% sure, 100% understanding
