Summary: The Maudsley Prescribing Guidelines In Psychiatry | 9781119442585 | David M Taylor, et al

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  • 1 Bipolair disorder

  • People with bipolair have ....intracellular concentration of sodium and calciumwhat does lithium for them?

    Heb higher intracellular concentration of sodium ( Na) en calcium ( CA)
    lithium can reduce these ( dus minder ca gaat naar intracellular)
  • 5 plasma levels Lithium

  • Plasma level Lithium  for the treatment of acute treatment of mania if necessarily adjunctive therapy with which agent(s)?

    0,8 -1,0 mmol /L
    singel agent antipsychotic with an evidence base for treating mania.  
  • Treatment of acute mania in patients already on long-term lithium

    If optimal then adding a dopamine antagonist , dopamine partial agonist of valproate
  • The highest tolerable lithium plasma level

    0,6-0,8 mmol/L , with the option to reduce it to 0,40-0,60 mmol/L in case of good response
    increase to 0,8-1,00 mmol /L in case of insufficient response en good tolerance. 
  • What is the aim of treatment Lithium

    Complete remission of both manic and depressive episodes
  • 7 adverse effects long term lithium therapy

  • 7.1 GI gastro intestinal

  • Gastrointestinal effects of Lithiumtherapy

    -Anorexia
    -nausea
    -diarrhoea
  • 7.2 fine tremor

  • Fine tremor treatment 

    Propranolol
  • 7.3 polyuria

  • Polyuria may occur frequently when Lithium is geven ---

    With twice daily dosing
  • 7.5 nephrogenic diabetes insipidus

  • Symptomen of diabetes insidiousare effects reversible and effect irreversible* symptomen ? 

    Dorst and polyuria
    * reversible if short en medium term
    * long term treatment ( >15 years)
  • 7.7 hypothyroidism

    This is a preview. There are 2 more flashcards available for chapter 7.7
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  • TFTs usually return to normal , when ?

    When lithium is discontinued
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