Granulomatous Inflammation
7 important questions on Granulomatous Inflammation
What is granulomatous inflammation?
Which cells are involved in granulomatous inflammation?
- Lymphocytes
- Giant cells - macrophages with giant nuclei
- Epithelioid macrophages
What are some causes of granulomatous inflammation?
- Foreign material
- Mycobacteria (not the same as mycoplasma)
- Fungi
- Delayed type hypersensitivity reactions
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What is the main factor leading to granulomatous inflammation?
What is the pathogenesis of granulomatous inflammation?
How does the immune response cause granulomatous inflammation?
What are the sequelae of granulomatous inflammation?
- Occupation of functional space (can lead to organ failure after enough space occupied)
- Impingement on vital structures
- Cachexia (consumption of body) via macrophages and their cytokines
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