GIT - Proton pum inhibitors (PUD) - Mucosal Protective Agents
3 important questions on GIT - Proton pum inhibitors (PUD) - Mucosal Protective Agents
What are some examples of mucosal protective agents (cytoprotectives)?
- Sucralfate
- Misoprostol
- Bismuth
- Polaprezine
- Carbenoxolone
What are some adverse effects of Carbenoxolone?
- Oedema
- Congestive heart failure
- Hypertension
- Hyperkalemia
- Hyperglycemia
What are the pharmacological effects of Carbenoxolone in promoting the healing of peptic ulcers?
- Increasing mucous secretion
- Increasing collagen formation at ulcer base
- Prolonging gastric epithelial life-span
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