Regions in the stomach - Fundic - Parietal glands

3 important questions on Regions in the stomach - Fundic - Parietal glands

What are parietal glands?

They are the secretory glands of the fundic region, located in gastric pits in fundus and body of stomach.

What types of parietal glands are present in the fundic region?

1. Mucous cells: secrete mucus
2. Parietal cells: secrete HCl & intrinsic factor
3. Chief cells: secrete zymogens
4. Enteroendocrine cells: secrete hormones into bloodstream (APUD cells, enterochromaffin cells)
5. Mast cells: secrete histamine and cytokines

What do mast cells do to contribute to acidity?

They secrete histamine to stimulate HCl secretion via H2 histamine receptors on parietal cells

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