Gut brain axis, the gut side - the biological role of microbial metabolites
6 important questions on Gut brain axis, the gut side - the biological role of microbial metabolites
What is the difference between MAMPs and PAMPs in innate immune recognition
How do short-chain fatty acids (SCFAs) affect tight junction protein expression in the intestinal barrier models?
Butyrate regultes the expression of tight junction proteins mediated by the activation of AMP-activated protein kinase (AMPK)
What is the link between mucus (mucin) production and luminal oxygen levels in the gut?
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What is the difference between primary and secondary bile acids, and which receptors do they activate?
Secondary bile acids are made by gut bacteria in colon, formed by modifying primary bile acids. They strongly activate TGR5
What is the function of AHR (aryl hydrocarbon receptors) in the gut and which metabolite activates AHR?
What are 4 different TRP circulating metabolites?
-tryptophol
-indole propionic acid
-indole acetic acid/tryptamien
-indoxyl sulfate: harmful!!
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