Biomedical mechanisms

5 important questions on Biomedical mechanisms

What are the 5 mechanisms of autism spectrum disorder and ketogenic interventions?

1 disrupted neurotransmitter balance
2 insulin resistance
3 mitochondrial dysfunction
4 epigenetic modification
5   microbiome

Which neurotransmitters are out of balance in autism spectrum disorder?

The neurotransmitters out of balance are glutamate (excitatory) and GABA (inhibitory)

What is insulin resistance?

When sugar is consumed repeatedly throughout the day, blood insulin levels rise continuously. Cells
receive constant signals to take up glucose. At a certain point, however, the cell has already taken in
sufficient glucose and no longer responds adequately. The receptor may stop passing on the signal, and
the number of receptors may decline.
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In which 3 ways does the ketogenic diet improve mitchondrial dysfunction?

1 Ketones enter cells through channels that are independent of insulin and are transported directly into the mitochondria.
2 stimulates the creation of new mitochondria
3  wrinkly shape normalize

What is the mechanism behind the positive effects of ketones on autism?

Ketones are balancing the the neurotransmitter glutamata (excitatory) and GABA (inhibitory). Ketones reduce glutamate activity and increase GABA production

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