Systemic Inflammatory Responses (SIRS)
4 important questions on Systemic Inflammatory Responses (SIRS)
What are the consequences of SIRS/sepsis?
- Fever
- Lethargy, anorexia
- Increased neutrophils and acute phase proteins in blood
- Systemic vasodilation, increased vascular permeability
- Shock, edema +/- fibrin +/- petechiae, and laminitis
- Tissue necrosis (e.g. Renal infarcts)
- Disseminated intravascular coagulation
- Consumptive coagulopathy, petechiae, tissue ischemia
What is SIRS (Systemic Inflammatory Response Syndrome)?
What are the outcomes of localized inflammatory responses?
- Cardinal signs of inflammation via vasodilation and vascular permeability
- Elimination of threat and wound healing via leukocyte activation
- Tissue damage from ischemia, free radicals, and proteases via leukocyte activation and endothelial activation & hypercoagulability (thrombosis)
- Higher grades + faster learning
- Never study anything twice
- 100% sure, 100% understanding
What are the negative outcomes of Systemic Inflammatory Responses?
- Tissue damage to kidney, liver, lung, heart, intestine, brain
- Consumptive coagulopathy and hemorrhage
The question on the page originate from the summary of the following study material:
- A unique study and practice tool
- Never study anything twice again
- Get the grades you hope for
- 100% sure, 100% understanding

















